Define simple protein, conjugated protein and the globular protein

  • Simple protein refers to protein that consists of only amino acids and does not contain any other substances. Example: collagen.
  • Conjugated protein is a protein that contains non-protein materials called prosthetic groups. Example: haemoglobin.
  • The globular protein is a polypeptide chain with tertiary or quaternary structures.  It is tightly coiled and folded into a spherical shape. Examples: enzymes, antibodies and some hormones. 

Amino acids are amphoteric molecules. Explain this statement.

  • Amphoteric molecules can act both as a base and an acid.
  • Amino acids have both acidic (carboxyl) and basic amino groups.
  • At high concentrations of hydrogen ions, the negatively charged carboxyl group will accept protons and become uncharged and the overall charge of the amino acids becomes positive.
  • At low concentration of hydrogen ions, the positively charged amino group loses its proton and the overall charge of molecule becomes negative. 

State factors that can cause the denaturation of proteins

  • Heat or radiation
  • Strong acids and alkalis
  • High salt concentration and heavy metals
  • Detergent and organic solvents
  • Mechanical force           

Compare between fibrous protein and globular protein

Similarities: Both are polypeptides.

Differences:

STPM Chemistry Syllabus 3rd Term

Chapter 14: Introduction to Organic Chemistry
14.1 Bonding of the carbon atoms: the shapes of ethane, ethane, ethyne and benzene molecules
14.2 General, empirical, molecular and structural formulae of organic compounds
14.3 Functional groups: classification and nomenclature
14.4 Isomerism: structural and stereoisomerism
14.5 Free radicals, nucleophiles and electrophiles
14.6 Molecular structure and its effect on physical properties
14.7 Inductive and resonance effect

Chapter 15: Hydrocarbons
15.1 Alkanes
15.2 Alkenes
15.3 Arenes

Chapter 16: Haloalkanes

Chapter 17: Hydroxy Compounds
17.1 Introduction to hydroxy compounds
17.2 Alcohols
17.3 Phenols

Chapter 18: Carbonyl Compounds

Chapter 19 Carboxylic Acids and their derivatives
19.1 Carboxylic acid
19.2 Acyl chlorides
19.3 Esters
19.4 Amides

Chapter 20: Amines, Amino Acids and Proteins
20.1 Amines
20.2 Amino acids
20.3 Proteins

Chapter 21: Polymers